Abstract: The purpose of this article is to explore the process of developing curriculum materials that involves the following stages, planning, drafting, editing, refining and reviewing course materials and also to explain what is involved at each stage by giving examples from an area of specialization. This article elaborated that lecturers could recognize the mindset of the student and that lecturers are conscious around the learning approaches and education plans. It was demonstrated in this article that lecturers perform the part as assessor as well for the valuation of education products. This further provided a surety that the lecturer can play different roles such as a developer, leader, constructor of information, manager, investigator, and systems analyst. This in conclusion means that lecturers could contribute an essential part in the development of curriculum expansion for lecturer teaching and students learning.

Abstract: Background/Objectives: The purpose of our study was to investigate the effect of formaldehyde (FA) on different parts of rat brain tissue. For this purpose, we determined BDNF and S100 expression levels by immunohistochemical methods and examined cell death via TUNEL method in rat brains exposed to subchronic FA doses. \nMethods: 24-Wistar albino rats were randomly divided into three groups: control group (CG, n=8), low dose FA group (LDG, n=8) and high dose FA group (HDG, n=8). LDG and HDG were exposed approximately 1 ppm and 10 ppm FA, respectively. Implementations lasted for 12 weeks. Inhalation period was 5 days a week and 4 hours a day. Finally, rats were sacrificed and brain tissues were gently removed. Brain tissue sections were stained with Haematoxylin-Eosin (H&E) for histopathologic examination whereas TUNEL method, BDNF and S100 antibodies were performed for immunohistochemical examination under light microscopy. \nResults: There was a significant decrease in body weights of rats belonging to HDG compared to the CG and LDG (p?0,05). In cortex, significant difference was detected between CG and LDG in terms of BDNF immunreactivity, whereas in thalamus and hippocampus, significant difference were seen between CG and both FA groups (p?0,05). Similarly, in cortex, there was a statistically significant difference between all groups for S100 immunreactivity. In thalamus and hippocampus, significant difference was only seen in LDG and HDG (p?0,05). In the TUNEL analysis, a statistically significant increase was observed in the apoptotic index values of both FA groups compared to the control group.\nConclusions: According to our findings, in FA groups, BDNF expression decreased while S100 expression increased. Apoptotic cell index results also supported increased S100 immunreactivity in FA groups. We suggested that FA exposure damaged to the different parts of brain tissue, caused neuronal-glial cell death and altered protein expressions.